Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.56 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | IAPP | P10997 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9419249 | 0.84 | KDM4E (0.41) | GABRA1GABRB2MCL1 | |
| SCHEMBL22306130 | 0.83 | GABRA1 (0.55) | GABRA1GABRB2DAOKAT6A | |
| SCHEMBL25380690 | 0.83 | HTR1A (0.47) | GABRA1GABRB2MEP1BIAPPHTR1A | |
| SCHEMBL4288658 | 0.79 | TAAR1 (0.46) | MEP1BADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL3080398 | 0.79 | MEP1B (0.46) | MEP1BADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL18122722 | 0.78 | MEP1B (0.42) | MEP1BIAPPADRB1ADRA2AADRB3 | |
| SCHEMBL28765037 | 0.78 | MEP1B (0.58) | MEP1BHTR1AMCL1 | |
| Bromide SCHEMBL923559 | 0.77 | TAAR1 (0.45) | MEP1BADRB1ADRA2AADRB3ADRA2B | |
| SCHEMBL18584816 | 0.77 | GABRA1 (0.50) | GABRA1GABRB2MEP1BDAOKAT6A | |
| SCHEMBL16962936 | 0.77 | GABRA1 (0.50) | GABRA1GABRB2DAOKAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12565489-B2 | Heterocyclyl pyrimidines and triazines as novel fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-03-03 | — | — | US | disclosed |
| US-12552748-B2 | Pyridine (thio)amides as fungicidal compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2026-02-17 | — | — | US | disclosed |
| EP-4149929-B1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AG (DE) | 2026-01-28 | — | — | EP | disclosed |
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-27 | — | — | US | disclosed |
| US-12520844-B2 | Triazine and pyrimidine (thio)amides as fungicidal compounds | BAYER AKTIENGESELLSCHAFT (DE) | 2026-01-13 | — | — | US | disclosed |
| US-20230348392-A1 | PYRIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-11-02 | — | — | US | disclosed |
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-21 | — | — | US | disclosed |
| US-20230278994-A1 | HETEROCYCLYL PYRIMIDINES AND TRIAZINES AS NOVEL FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-09-07 | — | — | US | disclosed |
| US-20230180756-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-15 | — | — | US | disclosed |
| CN-116157397-A | Heterocyclylpyridines as novel fungicides | 拜耳公司 | 2023-05-23 | — | — | CN | disclosed |
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | INTELLIKINE LLC | 2011-03-31 | — | — | US | disclosed |
| US-20100009963-A1 | KINASE ANTAGONISTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-01-14 | — | — | US | disclosed |
| US-7608639-B2 | Phenoxyether derivatives as PPAR modulators | ELI LILLY AND COMPANY (US) | 2009-10-27 | — | — | US | disclosed |
| US-7585868-B2 | Substituted pyrazolo[3,4-D]pyrimidines as kinase antagonists | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-09-08 | — | — | US | disclosed |
| US-7553867-B2 | Furan or thiophene derivative and medicinal use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-06-30 | — | — | US | disclosed |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-05-28 | — | — | US | disclosed |
| US-20070293516-A1 | Antagonists of a lipid kinase such as a PI3 kinase, protein tyrosine kinase, and/or protein serine-threonine kinases such as mTOR; 1-isopropyl-3-(3-methoxy-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2007-12-20 | — | — | US | disclosed |
| US-20070037812-A1 | Such as 3-{4-[3-(4-Chloro-2- phenoxy-phenoxy)- phenoxy]-2-methyl- phenyl}-propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis | ELI LILLY AND COMPANY (US) | 2007-02-15 | — | — | US | disclosed |
| EP-1675814-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005037763-A1 | PHENOXYETHER DERIVATIVES AS PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-04-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293516-A1 | Antagonists of a lipid kinase such as a PI3 kinase, protein tyrosine kinase, and/or protein serine-threonine kinases such as mTOR; 1-isopropyl-3-(3-methoxy-4-methylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine | MTOR, PI4KA, PIK3CA | GABRA1 3915/4885GABRB2 4168/4885MEP1B 1120/4885 |
| US-20230180756-A1 | TRIAZINE AND PYRIMIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | TPMT, TYMP, TPI1 | GABRA1 2784/4885GABRB2 2702/4885MEP1B 2896/4885 |
| US-12565489-B2 | Heterocyclyl pyrimidines and triazines as novel fungicides | CBR1, CBR3, NOX1 | GABRA1 1756/4885GABRB2 1253/4885MEP1B 1302/4885 |
| US-20230278994-A1 | HETEROCYCLYL PYRIMIDINES AND TRIAZINES AS NOVEL FUNGICIDES | DPYD, DPM1, DHPS | GABRA1 2842/4885GABRB2 2535/4885MEP1B 1912/4885 |
| US-20230348392-A1 | PYRIDINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | PNPO, TST, TPMT | GABRA1 2190/4885GABRB2 2173/4885MEP1B 4029/4885 |
| US-20100009963-A1 | KINASE ANTAGONISTS | MTOR, RPS6KA3, AKT3 | GABRA1 2019/4885GABRB2 1779/4885MEP1B 2760/4885 |
| US-20110077268-A1 | KINASE INHIBITORS AND METHODS OF USE | MAP3K20, MAP3K1, PDPK1 | GABRA1 3411/4885GABRB2 2836/4885MEP1B 1110/4885 |
| US-20230295138-A1 | HETEROCYCLYL PYRIDINES AS NOVEL FUNGICIDES | PNPO, CBR3, HPD | GABRA1 2068/4885GABRB2 1745/4885MEP1B 2350/4885 |
| US-20070037812-A1 | Such as 3-{4-[3-(4-Chloro-2- phenoxy-phenoxy)- phenoxy]-2-methyl- phenyl}-propionic acid; peroxisome proliferator activated receptor (PPAR); syndrome X, type II diabetes, hyperglycemia, hyperlipidemia, obesity, coagaulopathy, hypertension, arteriosclerosis | PPARA, PPARG, PPARD | GABRA1 450/4885GABRB2 559/4885MEP1B 4080/4885 |
| US-12534456-B2 | Heterocyclyl pyridines as novel fungicides | CBR1, CBR3, NOX1 | GABRA1 1217/4885GABRB2 818/4885MEP1B 1371/4885 |
| US-12552748-B2 | Pyridine (thio)amides as fungicidal compounds | CBR1, CBR3, TH | GABRA1 1292/4885GABRB2 1875/4885MEP1B 2745/4885 |
| US-20090137611-A1 | Fungicide N-Cyclopropyl-Sulfonylamide Derivatives | CYP51A1, ERG28, CBR3 | GABRA1 660/4885GABRB2 506/4885MEP1B 1019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.