Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylonitrile SCHEMBL9419944 | 0.84 | TSHR (0.50) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL11398066 | 0.81 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL7095062 | 0.80 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL11116930 | 0.78 | TSHR (0.37) | TSHRHPGDALDH1A1CYP3A4HCAR2 | |
| Acrylonitrile SCHEMBL5833833 | 0.76 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylonitrile SCHEMBL2146545 | 0.76 | TSHR (0.79) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL3395338 | 0.74 | TSHR (0.55) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Acrylic Acid Ethyl Ester SCHEMBL1091906 | 0.74 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL6754394 | 0.74 | TSHR (0.51) | TSHRHPGDALDH1A1CYP3A4ATM | |
| 1,1-Dichloroethene SCHEMBL8510978 | 0.73 | TSHR (0.69) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296555-A | Rubber composition of strong adhesion to metal and hose structure using the same | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1994-03-22 | — | — | US | claimed |
| US-5077108-A | Improved adhesion, heat, oil, solvent resistant | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1991-12-31 | — | — | US | claimed |
| US-5068137-A | Rubbery laminate and composite hose | THE YOKOHAMA RUBBER COMPANY (JP) | 1991-11-26 | — | — | US | claimed |
| US-5296555-A | Rubber composition of strong adhesion to metal and hose structure using the same | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0296890-B1 | HOSES | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-5158113-A | Heavy-duty hose having a multi-layered core tube | THE YOKOHAMA RUBBER CO., LTD. | 1992-10-27 | — | — | US | disclosed |
| US-5077108-A | Improved adhesion, heat, oil, solvent resistant | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1991-12-31 | — | — | US | disclosed |
| US-5068137-A | Rubbery laminate and composite hose | THE YOKOHAMA RUBBER COMPANY (JP) | 1991-11-26 | — | — | US | disclosed |
| EP-0296890-A2 | Hoses | THE YOKOHAMA RUBBER CO., LTD. (JP) | 1988-12-28 | — | — | EP | disclosed |