Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAPGEF4 | Q8WZA2 | 4/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 5/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003476 | 0.84 | CYP3A4 (0.50) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL1547849 | 0.84 | CYP3A4 (0.56) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL10913798 | 0.82 | CYP3A4 (0.40) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL31120437 | 0.82 | CYP3A4 (0.40) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL1019625 | 0.82 | CYP3A4 (0.43) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL31497683 | 0.82 | CYP3A4 (0.43) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL29380985 | 0.81 | CYP3A4 (0.48) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL31519176 | 0.79 | CYP3A4 (0.59) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL2260986 | 0.79 | CYP3A4 (0.59) | CYP3A4CHRM1ALOX15MAOATBXA2R | |
| SCHEMBL1006177 | 0.77 | CYP3A4 (0.43) | CYP3A4CHRM1ALOX15MAOATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0563033-A4 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON RES & TECH (US) | 1994-05-18 | — | — | EP | claimed |
| EP-0563033-A1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE. | CHEVRON RES & TECH (US) | 1993-10-06 | — | — | EP | claimed |
| WO-1992007820-A1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-05-14 | — | — | WO | claimed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | claimed |
| US-20170267717-A1 | Novel method for the production of 18F-labeled active esters and their application exemplified by the preparation of a PSMA-specific PET-tracer | MAX-PLANCK-GESELLSCHAFT ZUR FOERDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2017-09-21 | — | — | US | disclosed |
| EP-0563033-A4 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON RES & TECH (US) | 1994-05-18 | — | — | EP | disclosed |
| EP-0563033-A1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE. | CHEVRON RES & TECH (US) | 1993-10-06 | — | — | EP | disclosed |
| WO-1992007820-A1 | PROCESS FOR PREPARING 3-TRIFLUOROMETHYL BENZYL CHLORIDE | CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) | 1992-05-14 | — | — | WO | disclosed |
| US-4059610-A | Process for preparing isocyanic acid derivatives | KAO SOAP CO., LTD. (JA) | 1977-11-22 | — | — | US | disclosed |
| US-4056547-A | FROM AN ALKALI METAL OR AMMONIUM CYANATE AND A BENZYL CHLORIDE, CATALYST | KAO SOAP CO., LTD. (JA) | 1977-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267717-A1 | Novel method for the production of 18F-labeled active esters and their application exemplified by the preparation of a PSMA-specific PET-tracer | FGB, F13B, FAP | CYP3A4 1540/4885CHRM1 3864/4885ALOX15 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.