⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16286199 | 0.86 | ALDH1A1 (0.40) | — | |
| SCHEMBL10789479 | 0.85 | — | — | |
| SCHEMBL10784050 | 0.83 | EPHX1 (0.58) | — | |
| SCHEMBL19636154 | 0.82 | CASP2 (0.52) | — | |
| SCHEMBL10963060 | 0.81 | EPHX1 (0.61) | — | |
| SCHEMBL24388044 | 0.79 | — | — | |
| SCHEMBL8662639 | 0.78 | — | — | |
| S-Ethyl Propylcarbamothioate SCHEMBL10974251 | 0.77 | — | — | |
| SCHEMBL19608923 | 0.77 | — | — | |
| SCHEMBL21391475 | 0.75 | EPHX2 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0397012-B1 | Thiolcarbamate granule formulation | HODOGAYA CHEMICAL CO LTD (JP) | 1994-07-20 | — | — | EP | claimed |
| US-4497739-A | Synthesizing thiocarbamic acid esters | ANIC S.P.A. (IT) | 1985-02-05 | — | — | US | claimed |
| WO-2023083282-A1 | FUSED RING COMPOUND AS HPK1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2023-05-19 | — | — | WO | disclosed |
| US-20230135635-A1 | INHIBITORS OF ULK1/2 AND METHODS OF USING SAME | Sanford Burnham Prebys Medical Discovery Institute | 2023-05-04 | — | — | US | disclosed |
| US-11040978-B2 | Bicyclic heterocyclic derivatives as MNK1 and MNK2 modulators and uses thereof | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-06-22 | — | — | US | disclosed |
| US-20190315755-A1 | BICYCLIC HETEROCYCLIC DERIVATIVES AS MNK1 AND MNK2 MODULATORS AND USES THEREOF | AGENCY SCIENCE TECH & RES (SG) | 2019-10-17 | — | — | US | disclosed |
| US-20170335076-A1 | STRETCHABLE FILM AND METHOD FOR FORMING THE SAME, METHOD FOR MANUFACTURING COATED WIRING SUBSTRATE, AND STRETCHABLE WIRING FILM AND METHOD FOR MANUFACTURING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-11-23 | — | — | US | disclosed |
| US-20170190168-A1 | LITHOGRAPHIC PRINTING PLATES PRECURSORS COMPRISING A RADIATION SENSITIVE IMAGEABLE LAYER WITH A CROSSLINKED SURFACE | MYLAN GROUP (VN) | 2017-07-06 | — | — | US | disclosed |
| US-20170190168-A1 | LITHOGRAPHIC PRINTING PLATES PRECURSORS COMPRISING A RADIATION SENSITIVE IMAGEABLE LAYER WITH A CROSSLINKED SURFACE | MYLAN GROUP (VN) | 2017-07-06 | — | — | US | disclosed |
| US-4497739-A | Synthesizing thiocarbamic acid esters | ANIC S.P.A. (IT) | 1985-02-05 | — | — | US | disclosed |
| EP-0086017-A2 | Synthesizing thiocarbamic acid esters | ANIC S.p.A. (IT) | 1983-08-17 | — | — | EP | disclosed |