P-Xylene

P-Xylene

SCHEMBL9420802

Cc1ccc(C)c(C2CCCCC2)c1.Cc1ccc(C)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 1/20 0.49
DRD2 P14416 1/20 0.43
DRD4 P21917 1/20 0.43
DRD3 P35462 1/20 0.43
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
PSMB5 P28074 1/20 0.42
CHRNB2 P17787 1/20 0.39
CHRNA4 P43681 1/20 0.39
ALDH1A1 P00352 2/20 0.38
KDM4E B2RXH2 1/20 0.38
POLB P06746 1/20 0.38
TP53 P04637 2/20 0.38
MEN1 O00255 1/20 0.38
USP2 O75604 1/20 0.38
TSHR P16473 1/20 0.38
KMT2A Q03164 1/20 0.38
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
ATM Q13315 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7422191 0.98 PTGDR2 (0.50) PTGDR2DRD2DRD4DRD3NPC1
SCHEMBL19308494 0.96 PTGDR2 (0.47) PTGDR2DRD2DRD4DRD3NPC1
SCHEMBL16956272 0.87 DRD2 (0.47) PTGDR2DRD2DRD4DRD3NPC1
SCHEMBL1128140 0.82 PSMB5 (0.47) PTGDR2NPC1RAB9APSMB5CHRNB2
SCHEMBL25574304 0.81 PTGDR2 (0.39) PTGDR2DRD2DRD4DRD3NPC1
SCHEMBL11277728 0.80 ACMSD (0.42) PSMB5ALDH1A1KDM4ETP53KMT2A
SCHEMBL11295388 0.79 PSMB5 (0.45) PTGDR2NPC1RAB9APSMB5CHRNB2
SCHEMBL8788647 0.78 PTGDR2 (0.48) PTGDR2NPC1RAB9APSMB5CHRNB2
SCHEMBL10455337 0.78 NUDT1 (0.54) PTGDR2NPC1RAB9APSMB5CHRNB2
SCHEMBL2702248 0.78 NUDT1 (0.54) PTGDR2NPC1RAB9APSMB5CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1994004480-A1 PROCESS FOR PREPARING PHENYLTEREPHTHALIC ACID EASTMAN CHEMICAL COMPANY (US) 1994-03-03 WO disclosed