Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8313137 | 0.91 | MGAM (0.42) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL5605429 | 0.91 | — | — | |
| SCHEMBL284806 | 0.88 | — | — | |
| SCHEMBL29615225 | 0.88 | — | — | |
| SCHEMBL471892 | 0.88 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TP53ALOX15 | |
| SCHEMBL344175 | 0.88 | — | — | |
| SCHEMBL22598 | 0.88 | — | — | |
| Water SCHEMBL3622967 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL2655388 | 0.85 | — | — | |
| Methyl Alcohol SCHEMBL6027936 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294649-A | Hardening agent of magnesioum hydroxide or lightburned magnesium oxide and promoter of a nitrogen-containing heterocyclic compound | BORDEN, INC. (US) | 1994-03-15 | — | — | US | disclosed |
| US-5262495-A | Magnesium oxide or magnesium hydroxide hardeners to slow gelation | BORDEN, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5223554-A | Comprising anions of cyanate, formate, hypophosphite, nitrate, phosphite and sulfamate; used with magnesium hardening agent | BORDEN, INC. (US) | 1993-06-29 | — | — | US | disclosed |
| US-5214111-A | Comprising magnesium hydroxide hardener and retarder compounds, chelating agents; mixed with butyrolactone and water | BORDEN, INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5214079-A | Magnesium oxide or hydroxide | BORDEN, INC. (US) | 1993-05-25 | — | — | US | disclosed |
| US-5182346-A | Magnesium oxide or hydroxide, chelating agent | BORDEN, INC. (US) | 1993-01-26 | — | — | US | disclosed |
| US-5145913-A | Decrease solubility of magnesium oxide or magnesium hydroxide hardener | BORDEN, INC. (US) | 1992-09-08 | — | — | US | disclosed |
| US-5096983-A | Magnesium oxide and and ester as hardeners, retarder to inhibit hardening | BORDEN, INC. (US) | 1992-03-17 | — | — | US | disclosed |