Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22283511 | 0.81 | TAAR1 (0.42) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL28772261 | 0.78 | TAAR1 (0.44) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL8764960 | 0.78 | TAAR1 (0.44) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL19633319 | 0.74 | ADRA2C (0.44) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL8764335 | 0.74 | TAAR1 (0.41) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL8765111 | 0.74 | DPP4 (0.43) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL10904174 | 0.72 | TAAR1 (0.50) | TAAR1TSHR | |
| SCHEMBL297260 | 0.70 | DPP4 (0.46) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL11727695 | 0.70 | ADRA2C (0.46) | TAAR1CYP2D6ADRA2AADRA2CLMNA | |
| SCHEMBL705957 | 0.70 | TAAR1 (0.42) | TAAR1CYP2D6ADRA2AADRA2CLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9968866-B2 | Process for defoaming aqueous compositions containing surfactants | WACKER CHEMIE AG (DE) | 2018-05-15 | — | — | US | disclosed |
| EP-3007793-B1 | PROCESS FOR DEFOAMING AQUEOUS COMPOSITIONS CONTAINING SURFACTANTS, AND DEFOAMING FORMULATIONS | WACKER CHEMIE AG (DE) | 2017-04-26 | — | — | EP | disclosed |
| US-20160121239-A1 | PROCESS FOR DEFOAMING AQUEOUS COMPOSITIONS CONTAINING SURFACTANTS | WACKER CHEMIE AG (DE) | 2016-05-05 | — | — | US | disclosed |
| US-5332762-A | Aqueous emulsion | WACKER-CHEMIE GMBH (DE) | 1994-07-26 | — | — | US | disclosed |