Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.55 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10274627 | 0.77 | CHRM1 (0.54) | CHRM2CHRM3CHRM1CHRNB2CHRNA4 | |
| SCHEMBL28365544 | 0.75 | P2RX7 (0.35) | — | |
| SCHEMBL13592738 | 0.74 | CHRM2 (0.53) | CHRM2CHRM3CHRM1CHRNB2CHRNA4 | |
| SCHEMBL19035702 | 0.73 | QDPR (0.44) | — | |
| SCHEMBL12951109 | 0.72 | CHRM2 (0.54) | CHRM2CHRM3CHRM1CHRNB2CHRNA4 | |
| SCHEMBL30269977 | 0.71 | GPR119 (0.49) | — | |
| SCHEMBL8402584 | 0.71 | CHRM2 (1.00) | CHRM2CHRM3CHRM1CHRNB2CHRNA4 | |
| SCHEMBL27793790 | 0.70 | NISCH (0.42) | CHRNB2CHRNA4 | |
| SCHEMBL7613541 | 0.70 | CHRM1 (0.58) | CHRM2CHRM3CHRM1CHRNB2CHRNA4 | |
| SCHEMBL5139637 | 0.70 | CHRM2 (0.55) | CHRM2CHRM3CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994009787-A1 | SYNERGISTIC COMBINATION FOR THE THERAPY OF DEGENERATIVE AGEING DISEASES CONTAINING AN ADENOSINE ANTAGONIST AND A CHOLINOMIMETIC | BOEHRINGER INGELHEIM KG (DE) | 1994-05-11 | — | — | WO | claimed |
| WO-1994009787-A1 | SYNERGISTIC COMBINATION FOR THE THERAPY OF DEGENERATIVE AGEING DISEASES CONTAINING AN ADENOSINE ANTAGONIST AND A CHOLINOMIMETIC | BOEHRINGER INGELHEIM KG (DE) | 1994-05-11 | — | — | WO | disclosed |