SCHEMBL9422306

SCHEMBL9422306

CCCC(C)(C)c1cccc(C)c1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 2/20 0.60
GABRB2 P47870 2/20 0.60
ALDH1A1 P00352 3/20 0.46
TRPA1 O75762 2/20 0.42
CA2 P00918 1/20 0.42
CNR1 P21554 3/20 0.39
CNR2 P34972 3/20 0.39
ESR1 P03372 7/20 0.38
ESR2 Q92731 3/20 0.38
AR P10275 1/20 0.38
ATM Q13315 1/20 0.38
KDM4E B2RXH2 1/20 0.36
HPGD P15428 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP1A2 P05177 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
NLRP3 Q96P20 1/20 0.33
TSHR P16473 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1836851 0.88 CA2 (0.54) GABRA1GABRB2ALDH1A1CA2CNR1
SCHEMBL2914758 0.88 GABRA1 (0.55) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL6941224 0.86 CNR2 (0.55) GABRA1GABRB2ALDH1A1CNR1CNR2
SCHEMBL57364 0.85 GABRA1 (0.64) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL11212180 0.83 CA2 (0.65) GABRA1GABRB2ALDH1A1CA2ESR1
SCHEMBL5586637 0.83 CA2 (0.43) GABRA1GABRB2ALDH1A1TRPA1CA2
Butane SCHEMBL27461547 0.81 GABRA1 (0.84) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL7054598 0.80 GABRA1 (0.50) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL2911405 0.79 GABRA1 (0.62) GABRA1GABRB2ALDH1A1TRPA1CA2
Phenol SCHEMBL28227733 0.79 ESR1 (0.39) GABRA1GABRB2ALDH1A1CA2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0382559-B1 Polymer composition TONEN SEKIYUKAGAKU KK (JP) 1994-11-02 EP disclosed
US-4847434-A Biphenol process ETHYL CORPORATION (US) 1989-07-11 US disclosed