Sugi Predict

Sugi Predict / Compounds / SCHEMBL57364

SCHEMBL57364

SCHEMBL57364

CCC(C)(C)c1cccc(C)c1O

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GABRA1 P14867 2/20 0.64
▸ GABRB2 P47870 2/20 0.64
▸ ALDH1A1 P00352 3/20 0.50
▸ TRPA1 O75762 2/20 0.45
▸ CA2 P00918 1/20 0.45
▸ ATM Q13315 1/20 0.40
▸ KDM4E B2RXH2 1/20 0.38
▸ HPGD P15428 1/20 0.38
▸ HSD17B10 Q99714 1/20 0.38
▸ ESR1 P03372 2/20 0.36
▸ ESR2 Q92731 2/20 0.36
▸ CYP2C9 P11712 2/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ CYP2C19 P33261 1/20 0.35
▸ CNR1 P21554 2/20 0.35
▸ CNR2 P34972 2/20 0.35
▸ TSHR P16473 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ AR P10275 1/20 0.34
▸ NLRP3 Q96P20 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL56491 0.87 CA2 (0.58) GABRA1GABRB2ALDH1A1CA2ESR1
SCHEMBL5704783 0.85 GABRA1 (0.56) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL9422306 0.85 GABRA1 (0.60) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL5079537 0.84 GABRA1 (0.64) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL2911405 0.82 GABRA1 (0.62) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL4493446 0.82 CA2 (0.46) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL2916950 0.82 CA2 (0.71) GABRA1GABRB2ALDH1A1CA2ATM
SCHEMBL7150243 0.81 GABRA1 (0.60) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL2914758 0.80 GABRA1 (0.55) GABRA1GABRB2ALDH1A1TRPA1CA2
SCHEMBL7054598 0.80 GABRA1 (0.50) GABRA1GABRB2ALDH1A1TRPA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11834384-B2 Preparation of olefin by alcohol dehydration, and uses thereof for making polymer, fuel or fuel additive TOTAL MARKETING SERVICES (FR) 2023-12-05 — — US disclosed
US-20230057257-A1 Method for the Preparation of a Composition Enriched in 2-Methyl-But-2-Ene and Use for Making a Polymer AQUARIAN CREDIT FUNDING LLC 2023-02-23 — — US disclosed
EP-3765581-B1 PREPARATION OF OLEFIN BY ALCOHOL DEHYDRATION, AND USES THEREOF FOR MAKING POLYMER, FUEL OR FUEL ADDITIVE TOTALENERGIES ONETECH (FR) 2022-07-13 — — EP disclosed
CN-114650978-A Process for preparing 2-methyl-but-2-ene-rich compositions and use for preparing polymers 弗纳技术股份有限公司 2022-06-21 — — CN disclosed
US-11339239-B2 Polymer composition and use for making adhesive and article containing it FINA TECHNOLOGY, INC. (US) 2022-05-24 — — US disclosed
EP-3765536-B1 POLYMER COMPOSITION AND USE FOR MAKING ADHESIVE AND ARTICLE CONTAINING IT TOTAL RAFFINAGE CHIMIE (FR) 2022-02-23 — — EP disclosed
US-20210371563-A1 Polymer Composition and Use for Making Adhesive and Article Containing It AQUARIAN CREDIT FUNDING LLC 2021-12-02 — — US disclosed
EP-3521927-B1 POSITIVE WORKING LITHOGRAPHIC PRINTING PLATE PRECURSOR, METHOD FOR MANUFACTURING THE PRECURSOR AND METHOD FOR PRODUCING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORP (JP) 2021-10-27 — — EP disclosed
WO-2021053396-A1 METHOD FOR THE PREPARATION OF A COMPOSITION ENRICHED IN 2-METHYL-BUT-2-ENE AND USE FOR MAKING A POLYMER TOTAL RAFFINAGE CHIMIE (FR) 2021-03-25 — — WO disclosed
EP-3792234-A1 METHOD FOR THE PREPARATION OF 2-METHYL-BUT-2-ENE Total Raffinage Chimie (FR) 2021-03-17 — — EP disclosed
US-6717020-B2 HIGH YIELD REACTION OF PHENOLS AND UNSATURATED ALCOHOLS IN PRESENCE OF SUCH AS TITANIUM TETRAETHOXIDE AND SODIUM METHOXIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-04-06 — — US disclosed
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED 2003-10-16 — — US disclosed
EP-1348686-A1 Method of producing p-hydroxyphenylalkanols SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-10-01 — — EP disclosed
EP-0733695-A1 Mannich base derivatives, and the production and uses thereof ETHYL CORPORATION (US) 1996-09-25 — — EP disclosed
US-5558683-A FUEL ADDITIVE ETHYL CORPORATION (US) 1996-09-24 — — US disclosed
US-5387266-A Detergent-dispersant additives for fuels and lubricants ETHYL CORPORATION (US) 1995-02-07 — — US disclosed
US-5279917-A Printing plate KONICA CORPORATION (JP) 1994-01-18 — — US disclosed
EP-0512845-A2 Light-sensitive planographic printing plate and light-sensitive composition KONICA CORPORATION (JP) 1992-11-11 — — EP disclosed
US-4877902-A REACTING 2,6-DIALKYLPHENOL WITH SULFUR CHLORIDE AT LOW TEMPERATURE ETHYL CORPORATION (US) 1989-10-31 — — US disclosed
US-4219570-A Insect repellents and a method of repelling insects AJINOMOTO COMPANY, INCORPORATED (JP) 1980-08-26 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030195379-A1 Method of producing p-Hydroxyphenylalkanols ADH1C, NR1H3, ADH5 GABRA1 4187/4885GABRB2 4176/4885ALDH1A1 135/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.