Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALAD | P13716 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899479 | 0.84 | GSK3B (0.61) | MEN1KMT2AGSK3BALDH1A1MAPT | |
| Bromide SCHEMBL8935164 | 0.82 | GSK3B (0.59) | MEN1KMT2AGSK3BALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8935203 | 0.82 | GSK3B (0.59) | MEN1KMT2AGSK3BALDH1A1MAPT | |
| SCHEMBL9422580 | 0.81 | ALDH1A1 (0.47) | MEN1KMT2AGSK3BALDH1A1ALOX15 | |
| SCHEMBL9422581 | 0.73 | GSK3B (0.42) | MEN1KMT2AGSK3BALDH1A1MAPK1 | |
| SCHEMBL4056583 | 0.72 | DAO (0.43) | MEN1KMT2AGSK3BALDH1A1ALOX15 | |
| SCHEMBL4059204 | 0.72 | DAO (0.43) | MEN1KMT2AGSK3BALDH1A1ALOX15 | |
| SCHEMBL5010509 | 0.70 | GSK3B (0.59) | MEN1KMT2AGSK3BALDH1A1MAPK1 | |
| Tibrofan SCHEMBL2110124 | 0.70 | MEN1 (1.00) | MEN1KMT2AGSK3BALDH1A1MAPK1 | |
| 4-Bromoaniline SCHEMBL27598179 | 0.69 | ALDH1A1 (0.65) | MEN1KMT2AALDH1A1ALOX15MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6220043-A | — | — | None | — | — | JP | disclosed |
| JP-H06220043-A | SUBSTITUTED THIOPHENECARBOXAMIDE | BAYER AG | 1994-08-09 | — | — | JP | disclosed |