Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 9/20 | 0.61 |
| ▸ | AGTR2 | P50052 | 9/20 | 0.61 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055933 | 0.88 | AGTR2 (0.66) | AGTR1AGTR2TLR7 | |
| SCHEMBL7056945 | 0.83 | KDM4E (0.52) | AGTR1AGTR2 | |
| SCHEMBL9422855 | 0.80 | AGTR1 (0.60) | AGTR1AGTR2TLR7 | |
| SCHEMBL9422812 | 0.80 | AGTR1 (0.58) | AGTR1AGTR2TLR7 | |
| SCHEMBL9422766 | 0.78 | AGTR2 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7671655 | 0.78 | AGTR1 (0.83) | AGTR1AGTR2 | |
| SCHEMBL9422897 | 0.78 | AGTR1 (0.86) | AGTR1AGTR2 | |
| SCHEMBL9200811 | 0.76 | AGTR1 (1.00) | AGTR1AGTR2TLR7 | |
| SCHEMBL9125532 | 0.76 | AGTR1 (0.80) | AGTR1AGTR2TLR7 | |
| SCHEMBL8081240 | 0.76 | AGTR2 (0.73) | AGTR1AGTR2TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294631-A | Substituted benzimidazoles useful as angiotension II receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0525129-A4 | SUBSTITUTED BENZIMIDAZOLES | — | 1993-03-24 | — | — | EP | disclosed |
| EP-0525129-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016313-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-31 | — | — | WO | disclosed |