Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422775 | 0.87 | KDM4E (0.53) | AGTR1AGTR2 | |
| SCHEMBL9422824 | 0.84 | AGTR2 (0.45) | AGTR1AGTR2 | |
| SCHEMBL9422906 | 0.80 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL6170161 | 0.78 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9422841 | 0.78 | KDM4E (0.54) | AGTR1AGTR2 | |
| SCHEMBL6170907 | 0.76 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9422780 | 0.74 | KDM4E (0.52) | AGTR1AGTR2 | |
| SCHEMBL15660720 | 0.72 | RARB (0.54) | AGTR1AGTR2 | |
| SCHEMBL6170644 | 0.72 | AGTR2 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9422890 | 0.72 | KDM4E (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294631-A | Substituted benzimidazoles useful as angiotension II receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0525129-A4 | SUBSTITUTED BENZIMIDAZOLES | — | 1993-03-24 | — | — | EP | disclosed |
| EP-0525129-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016313-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-31 | — | — | WO | disclosed |