Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.47 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9422766 | 0.94 | AGTR2 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7055933 | 0.83 | AGTR2 (0.66) | AGTR1AGTR2 | |
| SCHEMBL9422987 | 0.82 | AGTR2 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9422984 | 0.77 | KDM4E (0.53) | AGTR1AGTR2 | |
| SCHEMBL9754985 | 0.76 | AGTR2 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9422812 | 0.75 | AGTR1 (0.58) | AGTR1AGTR2 | |
| SCHEMBL9422906 | 0.74 | AGTR1 (0.49) | PPARGAGTR1AGTR2 | |
| SCHEMBL9192213 | 0.72 | AGTR2 (0.58) | AGTR1AGTR2 | |
| SCHEMBL20077276 | 0.72 | SMN1; SMN2 (0.53) | PPARG | |
| SCHEMBL9422752 | 0.72 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5294631-A | Substituted benzimidazoles useful as angiotension II receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0525129-A4 | SUBSTITUTED BENZIMIDAZOLES | — | 1993-03-24 | — | — | EP | disclosed |
| EP-0525129-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1993-02-03 | — | — | EP | disclosed |
| WO-1991016313-A1 | SUBSTITUTED BENZIMIDAZOLES | SMITHKLINE BEECHAM CORPORATION (US) | 1991-10-31 | — | — | WO | disclosed |