Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ACR | P10323 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423063 | 0.88 | HTT (0.67) | HTTALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL9429043 | 0.87 | HTT (0.65) | HTTALDH1A1MAPTTP53LMNA | |
| SCHEMBL9423254 | 0.85 | HTT (0.63) | HTTALDH1A1MAPTTP53PTGS2 | |
| SCHEMBL9422978 | 0.85 | HTT (0.66) | HTTALDH1A1MAPTTP53PTGS2 | |
| SCHEMBL8376637 | 0.84 | LMNA (0.57) | HTTALDH1A1PTGS2SMN1; SMN2TSHR | |
| SCHEMBL9428918 | 0.83 | HTT (0.67) | HTTALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL9429860 | 0.81 | HTT (0.64) | HTTALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL9423028 | 0.80 | HTT (0.62) | HTTALDH1A1MAPTTP53SMN1; SMN2 | |
| SCHEMBL9428786 | 0.80 | HTT (0.65) | HTTALDH1A1MAPTTP53PTGS2 | |
| SCHEMBL9423132 | 0.79 | HTT (0.64) | HTTALDH1A1MAPTTP53PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5371099-A | Antiinflammatory agents | ROUSSEL-UCLAF (FR) | 1994-12-06 | — | — | US | disclosed |