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Sugi Predict / Compounds / SCHEMBL9423014

SCHEMBL9423014

SCHEMBL9423014

CN(C)/N=C/c1cc(-n2c(=O)cc(C(F)(F)F)n(C)c2=O)ccc1Cl

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.34
▸ MAPT P10636 3/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ PKM P14618 1/20 0.31
▸ HTT P42858 2/20 0.31
▸ KMT2A Q03164 2/20 0.31
▸ TDP1 Q9NUW8 2/20 0.31
▸ MEN1 O00255 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ BRD9 Q9H8M2 1/20 0.31
▸ MAPK1 P28482 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9423017 1.00 L3MBTL1 (0.34) L3MBTL1MAPTALDH1A1PKMHTT
SCHEMBL9423359 0.88 ALDH1A1 (0.36) MAPTALDH1A1HTTBRD9
SCHEMBL9423357 0.88 ALDH1A1 (0.36) MAPTALDH1A1HTTBRD9
SCHEMBL7752592 0.86 NOTUM (0.31) BRD9
SCHEMBL7752587 0.86 NOTUM (0.31) BRD9
SCHEMBL7894620 0.85 ALDH1A1 (0.35) L3MBTL1MAPTALDH1A1PKMTDP1
SCHEMBL7756166 0.83 BRD9 (0.33) BRD9
SCHEMBL9230127 0.83 — —
SCHEMBL7756160 0.83 BRD9 (0.33) BRD9
SCHEMBL7530298 0.79 NOTUM (0.33) BRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5336663-A 3-aryluracil derivatives and their use for weed control CIBA-GEIGY CORPORATION (US) 1994-08-09 — — US disclosed