SCHEMBL9423359

SCHEMBL9423359

Cn1c(C(F)(F)F)cc(=O)n(-c2ccc(Cl)c(C=NO)c2)c1=O

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
MAPT P10636 2/20 0.36
GAA P10253 1/20 0.36
NOTUM Q6P988 2/20 0.32
BRD9 Q9H8M2 1/20 0.31
HPGD P15428 2/20 0.31
HTT P42858 1/20 0.31
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9423357 1.00 ALDH1A1 (0.36) ALDH1A1MAPTGAANOTUMBRD9
SCHEMBL9423017 0.88 L3MBTL1 (0.34) ALDH1A1MAPTBRD9HTT
SCHEMBL9423014 0.88 L3MBTL1 (0.34) ALDH1A1MAPTBRD9HTT
SCHEMBL7752587 0.87 NOTUM (0.31) NOTUMBRD9
SCHEMBL7752592 0.87 NOTUM (0.31) NOTUMBRD9
SCHEMBL7894620 0.86 ALDH1A1 (0.35) ALDH1A1MAPTNOTUMBRD9HPGD
SCHEMBL7756160 0.84 BRD9 (0.33) BRD9
SCHEMBL7756166 0.84 BRD9 (0.33) BRD9
SCHEMBL9230127 0.84
SCHEMBL7530298 0.82 NOTUM (0.33) NOTUMBRD9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5336663-A 3-aryluracil derivatives and their use for weed control CIBA-GEIGY CORPORATION (US) 1994-08-09 US disclosed
EP-0542685-A1 3-Aryluracile derivatives and their use against weeds CIBA-GEIGY AG (CH) 1993-05-19 EP disclosed