Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423043 | 0.89 | ALDH1A1 (0.38) | NOTUMGAALMNAALDH1A1L3MBTL1 | |
| SCHEMBL9423186 | 0.89 | GSK3B (0.37) | NOTUMGAALMNAALDH1A1L3MBTL1 | |
| SCHEMBL27573944 | 0.86 | ALDH1A1 (0.50) | NOTUMGAAALDH1A1L3MBTL1MAPK1 | |
| SCHEMBL6465176 | 0.82 | GAA (0.43) | NOTUMGAALMNAALDH1A1L3MBTL1 | |
| SCHEMBL9423189 | 0.81 | GAA (0.35) | ACHENOTUMGAALMNAALDH1A1 | |
| SCHEMBL9423206 | 0.80 | ACHE (0.34) | ACHEGAAALDH1A1MAPTRAB9A | |
| SCHEMBL7524310 | 0.75 | PLA2G10 (0.31) | GAALMNAALDH1A1NPC1RAB9A | |
| SCHEMBL9423249 | 0.74 | GAA (0.33) | ACHEGAALMNAALDH1A1L3MBTL1 | |
| SCHEMBL7526227 | 0.73 | NOTUM (0.34) | NOTUMGAALMNAALDH1A1MAPT | |
| SCHEMBL7524485 | 0.73 | NOTUM (0.34) | NOTUMGAALMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542685-A1 | 3-Aryluracile derivatives and their use against weeds | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | claimed |
| US-5336663-A | 3-aryluracil derivatives and their use for weed control | CIBA-GEIGY CORPORATION (US) | 1994-08-09 | — | — | US | disclosed |
| EP-0542685-A1 | 3-Aryluracile derivatives and their use against weeds | CIBA-GEIGY AG (CH) | 1993-05-19 | — | — | EP | disclosed |