Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KLK3 | P07288 | 4/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | RPA1 | P27694 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423275 | 0.83 | SMN1; SMN2 (0.49) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL9121751 | 0.83 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL10112053 | 0.74 | SMN1; SMN2 (0.59) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL4049437 | 0.74 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL27139267 | 0.74 | HDAC3 (0.53) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL5333233 | 0.70 | HDAC3 (0.55) | MAPTALDH1A1KDM4EHPGDHDAC1 | |
| SCHEMBL10103714 | 0.69 | SMN1; SMN2 (0.54) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL9124745 | 0.69 | SMN1; SMN2 (0.47) | LMNASMN1; SMN2KMT2AMEN1NPC1 | |
| SCHEMBL9423191 | 0.69 | PTGS1 (0.56) | KMT2AMEN1MAPTALDH1A1KDM4E | |
| SCHEMBL13737397 | 0.68 | ALDH1A1 (0.78) | LMNASMN1; SMN2KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358947-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-10-25 | — | — | US | disclosed |