Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 7/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 4/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9123670 | 0.84 | PTGS1 (0.54) | PTGS1PTGS2HSD17B10CYP1A2MAPK1 | |
| SCHEMBL3393181 | 0.73 | KDM4E (0.53) | PTGS1PTGS2HSD17B10CYP1A2MAPK1 | |
| SCHEMBL25407314 | 0.71 | PTGS1 (0.56) | PTGS1PTGS2HSD17B10KMT2AKDM4E | |
| SCHEMBL25407369 | 0.70 | PTGS1 (0.55) | PTGS1PTGS2HSD17B10KDM4EMAPT | |
| SCHEMBL9423332 | 0.69 | LMNA (0.49) | HSD17B10CYP1A2MAPK1CYP2C19KMT2A | |
| SCHEMBL20488661 | 0.68 | TDP1 (0.57) | PTGS1HSD17B10KMT2AKDM4EMEN1 | |
| SCHEMBL2212356 | 0.68 | PTGS1 (0.76) | PTGS1PTGS2HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL13425981 | 0.67 | PTGS2 (0.46) | PTGS1PTGS2HSD17B10CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL3169074 | 0.67 | PTGS1 (0.74) | PTGS1PTGS2HSD17B10CYP1A2CYP2C19 | |
| SCHEMBL930406 | 0.67 | ADORA2A (0.63) | ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5358947-A | Treating hypertension, congestive heart failure | AMERICAN CYANAMID COMPANY (US) | 1994-10-25 | — | — | US | disclosed |