Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.36 |
| ▸ | SCN1A | P35498 | 3/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.36 |
| ▸ | HRH1 | P35367 | 5/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423327 | 0.80 | CHRM2 (0.59) | TSHRKDM4ESLC6A2SLC6A4CHRM2 | |
| SCHEMBL9423792 | 0.78 | CCR5 (0.44) | SLC6A2SLC6A4HRH3LMNAKMT2A | |
| SCHEMBL11619843 | 0.75 | ACHE (0.53) | KDM4ELMNACYP2C19NPSR1SCD | |
| SCHEMBL31143787 | 0.75 | ACHE (0.53) | KDM4ELMNACYP2C19NPSR1SCD | |
| SCHEMBL31143655 | 0.75 | ACHE (0.53) | KDM4ELMNACYP2C19NPSR1SCD | |
| SCHEMBL23610053 | 0.75 | ACHE (0.53) | KDM4ELMNACYP2C19NPSR1SCD | |
| SCHEMBL282482 | 0.72 | — | — | |
| SCHEMBL5105719 | 0.69 | GAA (0.46) | KDM4EALDH1A1NFKB1KMT2ABRD4 | |
| SCHEMBL12772066 | 0.68 | TDP1 (0.36) | TSHRKDM4EALDH1A1SLC6A2SLC6A4 | |
| SCHEMBL23610054 | 0.68 | SCD (0.53) | TSHRKDM4ESLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |