Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9423666 | 0.78 | LMNA (0.49) | CCR5LMNASMN1; SMN2POLBHRH3 | |
| SCHEMBL9423716 | 0.78 | TSHR (0.37) | LMNAKMT2ABRD4HRH3SLC6A2 | |
| SCHEMBL282482 | 0.73 | — | — | |
| SCHEMBL19381538 | 0.69 | GAA (0.41) | CCR5LMNAPOLBMEN1KMT2A | |
| SCHEMBL1978915 | 0.69 | CNR2 (0.48) | LMNASMN1; SMN2POLBNPC1CNR2 | |
| SCHEMBL282542 | 0.69 | CCR5 (0.57) | CCR5LMNAPOLBMEN1KMT2A | |
| SCHEMBL19381533 | 0.67 | CCR5 (0.33) | CCR5LMNASMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL7609582 | 0.66 | ELANE (0.43) | AOC3LMNAPOLB | |
| SCHEMBL3394593 | 0.66 | FDPS (0.47) | LMNASMN1; SMN2POLBNPC1FDPS | |
| SCHEMBL2521226 | 0.66 | IDO1 (0.44) | AOC3LMNASMN1; SMN2POLBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5308840-A | Antioxidants, antiallergens and antiinflammatory agents | GREEN CROSS CORPORATION (JP) | 1994-05-03 | — | — | US | disclosed |
| EP-0508334-A2 | Novel aminophenol derivatives and pharmaceutical compositions thereof | THE GREEN CROSS CORPORATION (JP) | 1992-10-14 | — | — | EP | disclosed |