Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 14/20 | 0.66 |
| ▸ | CA1 | P00915 | 11/20 | 0.66 |
| ▸ | CA9 | Q16790 | 10/20 | 0.66 |
| ▸ | CA12 | O43570 | 10/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CA7 | P43166 | 6/20 | 0.56 |
| ▸ | CA5A | P35218 | 5/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.56 |
| ▸ | CA3 | P07451 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL84516 | 0.98 | CA2 (0.68) | CA2CA1CA9CA12ALDH1A1 | |
| Fluoride SCHEMBL28353367 | 0.95 | CA2 (0.66) | CA2CA1CA9CA12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL3532247 | 0.95 | CA2 (0.66) | CA2CA1CA9CA12ALDH1A1 | |
| Benzenesulfonamide SCHEMBL9819524 | 0.83 | CA2 (0.67) | CA2CA1CA9CA12ALDH1A1 | |
| Sulfanilamide SCHEMBL27568655 | 0.82 | CA2 (0.63) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL8248221 | 0.82 | ALDH1A1 (0.62) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL1186051 | 0.82 | ALDH1A1 (0.62) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL1790668 | 0.82 | ALDH1A1 (0.62) | CA2CA1CA9CA12ALDH1A1 | |
| SCHEMBL672750 | 0.80 | CA2 (1.00) | CA2CA1CA9CA12CA7 | |
| SCHEMBL12112205 | 0.80 | ALDH1A1 (0.60) | CA2CA1CA9CA12ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5292740-A | Sulfonamides | HOFFMANN-LA ROCHE INC. (US) | 1994-03-08 | — | — | US | disclosed |
| US-5270313-A | Treatment of circulatory disorders | HOFFMANN-LA ROCHE INC. (US) | 1993-12-14 | — | — | US | disclosed |