SCHEMBL9423828

SCHEMBL9423828

C#CC(I)N(CCCCCC)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 2/20 0.38
GPR84 Q9NQS5 10/20 0.34
PPARG P37231 7/20 0.34
PPARD Q03181 7/20 0.34
PPARA Q07869 7/20 0.34
HDAC11 Q96DB2 5/20 0.34
TSHR P16473 4/20 0.34
PTPN1 P18031 3/20 0.34
ALDH1A1 P00352 2/20 0.34
TLR2 O60603 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
FABP4 P15090 2/20 0.34
FFAR1 O14842 2/20 0.34
SLC22A6 Q4U2R8 1/20 0.34
SLC22A8 Q8TCC7 1/20 0.34
MEN1 O00255 1/20 0.34
ESR1 P03372 1/20 0.34
ALOX15 P16050 1/20 0.34
PDE4A P27815 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL536192 0.93 CA12 (0.33) EPHX2
SCHEMBL1759008 0.74 EPHX2 (0.54) EPHX2GPR84PPARGPPARDPPARA
SCHEMBL8961040 0.74 ALDH1A1 (0.36) ALDH1A1HSD17B10
SCHEMBL10780249 0.71 ADH1C (0.39) TSHR
SCHEMBL29201414 0.70 MAPT (0.44) EPHX2GPR84PPARGPPARDPPARA
SCHEMBL932565 0.69 CA1 (0.36) EPHX2GPR84PPARGPPARDPPARA
SCHEMBL1416635 0.69 EPHX1 (0.43) EPHX2GPR84PPARGPPARDPPARA
SCHEMBL15225281 0.69 FAAH (0.40) EPHX2GPR84PPARGPPARDPPARA
SCHEMBL11355835 0.69 EPHX2 (0.42) EPHX2GPR84PPARGPPARDPPARA
SCHEMBL1416748 0.69 EPHX1 (0.43) EPHX2GPR84PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106103444-B Microbicidal heterobicyclic derivatives 先正达参股股份有限公司 2019-03-12 CN disclosed
CN-108349915-A Microbiocidal aniline derivatives 先正达参股股份有限公司 2018-07-31 CN disclosed
US-5354777-A Cyanoalkene derivatives, process for their preparation, and their use as microbicide for the protection of materials BAYER AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed