SCHEMBL9423904

SCHEMBL9423904

Oc1c(CCc2ccccc2)cccc1CCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.48
DRD2 P14416 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
KCNH2 Q12809 1/20 0.46
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
ALDH1A1 P00352 2/20 0.46
ADRB2 P07550 1/20 0.46
MPO P05164 1/20 0.46
MAOA P21397 2/20 0.45
MAOB P27338 2/20 0.45
FFAR1 O14842 1/20 0.45
HTT P42858 1/20 0.45
BID P55957 1/20 0.44
BCL2L1 Q07817 1/20 0.44
MCL1 Q07820 1/20 0.44
BAK1 Q16611 1/20 0.44
HPGD P15428 1/20 0.44
ALOX15 P16050 1/20 0.44
ALOX12 P18054 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9052787 0.90 GABRA1 (0.65) HTR1ADRD2GABRA1GABRB2ALDH1A1
SCHEMBL1426622 0.89 IAPP (0.52) MPOBIDBCL2L1MCL1BAK1
SCHEMBL30335940 0.87 AKR1B1 (0.55) TDP1ALDH1A1ADRB2FFAR1HTT
SCHEMBL20696108 0.86 BID (0.54) TDP1MPOMAOAMAOBBID
SCHEMBL8406787 0.86 HTR1A (0.46) HTR1ADRD2TDP1ALDH1A1ADRB2
SCHEMBL8432324 0.86 NPC1 (0.44) HTR1ADRD2TDP1ALDH1A1ADRB2
SCHEMBL5085770 0.86 ALDH1A1 (0.48) HTR1ADRD2ALDH1A1HTTBCL2L1
SCHEMBL22721262 0.85 BID (0.62) MPOMAOAMAOBBIDBCL2L1
SCHEMBL8409212 0.84 PDCD1 (0.46) HTR1ADRD2TDP1ALDH1A1FFAR1
SCHEMBL13903972 0.84 TDP1 (0.46) HTR1ADRD2TDP1ALDH1A1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5312461-A Dihydrocarbyl substituted phenylenediamine-derived phenolic products as antioxidants MOBIL OIL CORPORATION (US) 1994-05-17 US claimed
US-5207939-A Lubricants with oxidation resistance MOBIL OIL CORPORATION (US) 1993-05-04 US claimed
EP-4192922-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF Hercules LLC (US) 2023-06-14 EP disclosed
EP-4192923-A1 HYDROPHOBICALLY-MODIFIED ASSOCIATIVE THICKENER POLYMERS PROCESS FOR THE PREPARATION AND USES THEREOF Hercules LLC (US) 2023-06-14 EP disclosed
CN-104870514-B Styrenated phenols useful as hardeners or plasticizers for epoxy resins 锦湖石油化学株式会社 2019-10-01 CN disclosed
US-5312461-A Dihydrocarbyl substituted phenylenediamine-derived phenolic products as antioxidants MOBIL OIL CORPORATION (US) 1994-05-17 US disclosed
US-5207939-A Lubricants with oxidation resistance MOBIL OIL CORPORATION (US) 1993-05-04 US disclosed
US-3962180-A COPPER, MANGANESE OR COBALT AND AN AMINE CATALYST MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1976-06-08 US disclosed