SCHEMBL94245

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3584765	0.87	NAMPT (0.61)	NAMPTSLC6A7PDK1PDK2PDK3
	SCHEMBL25160524	0.86	NAMPT (0.60)	NAMPTSLC6A7PDK1PDK2PDK3
	SCHEMBL20639683	0.86	GPR183 (0.64)	NAMPTSLC6A7PDK1PDK2PDK3
	SCHEMBL25160076	0.86	GPR183 (0.64)	NAMPTSLC6A7PDK1PDK2PDK3
	SCHEMBL20347007	0.86	LMNA (0.67)	NAMPTSLC6A7POLBLMNAMEN1
	SCHEMBL7954884	0.83	SLC6A7 (0.63)	NAMPTSLC6A7PDK1PDK2PDK3
	SCHEMBL95503	0.81	HSP90AA1 (0.74)	NAMPTSLC6A7LMNAMEN1KMT2A
	SCHEMBL94420	0.81	MEN1 (0.74)	SLC6A7POLBLMNAMEN1KMT2A
	SCHEMBL95296	0.78	SMN1; SMN2 (0.67)	NAMPTSLC6A7POLBLMNAMEN1
	SCHEMBL94700	0.78	MEN1 (0.60)	NAMPTSLC6A7MEN1KMT2AHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.