Piperonal

Piperonal

SCHEMBL9424697

COC(C)OC.O=Cc1ccc2c(c1)OCO2

nearest known ligand 0.72

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.72
TDP1 Q9NUW8 3/20 0.72
HSD17B10 Q99714 1/20 0.72
KDM4E B2RXH2 2/20 0.51
CYP3A4 P08684 2/20 0.50
ATM Q13315 1/20 0.50
CYP1A2 P05177 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
GABRA1 P14867 2/20 0.45
GABRB2 P47870 2/20 0.45
PGR P06401 1/20 0.44
AR P10275 1/20 0.44
MAOA P21397 1/20 0.44
SLC6A2 P23975 1/20 0.44
PDE4A P27815 1/20 0.44
KDR P35968 1/20 0.44
SLC6A3 Q01959 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperonal SCHEMBL28534378 0.89 ALDH1A1 (0.85) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL1864802 0.85 ALDH1A1 (1.00) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL29411164 0.85 ALDH1A1 (1.00) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL29318 0.85 ALDH1A1 (1.00) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL5958791 0.83 ALDH1A1 (0.96) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL28017062 0.83 ALDH1A1 (0.96) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL873083 0.81 ALDH1A1 (0.62) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Cuminaldehyde SCHEMBL7548603 0.81 ALDH1A1 (0.72) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL20184609 0.81 ALDH1A1 (0.72) ALDH1A1TDP1HSD17B10KDM4ECYP3A4
Piperonal SCHEMBL1774149 0.80 ALDH1A1 (0.82) ALDH1A1TDP1HSD17B10KDM4ECYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101299987-B Multi-phase personal care compositions comprising stable perfume compositions PROCTER & GAMBLE 2014-05-07 CN claimed
CN-101299987-A Multi-phase personal care compositions comprising stable perfume compositions PROCTER & GAMBLE (US) 2008-11-05 CN claimed
JP-63079894-A None JP disclosed
CN-104937149-A Polyurethane fiber TORAY OPELONTEX CO LTD 2015-09-23 CN disclosed
CN-101299987-B Multi-phase personal care compositions comprising stable perfume compositions PROCTER & GAMBLE 2014-05-07 CN disclosed
CN-103189076-A Deodorant composition for sulfides TAKASAGO PERFUMERY CO LTD 2013-07-03 CN disclosed
CN-101299987-A Multi-phase personal care compositions comprising stable perfume compositions PROCTER & GAMBLE (US) 2008-11-05 CN disclosed
US-5286602-A Acid-cleavable compounds, positive-working radiation-sensitive mixture containing these compounds, and radiation-sensitive recording material produced with this mixture HOECHST AKTIENGESELLSCHAFT (DE) 1994-02-15 US disclosed
JP-S6379894-A METHYL-4,6-0-3',4'-METHYLENEDIOXYBENZYLIDENE-ALPHA-D-GLY-COSIDE KANEBO LTD 1988-04-09 JP disclosed