Piperonal

Piperonal

SCHEMBL873083

CCCC.CCOC(C)OCC.O=Cc1ccc2c(c1)OCO2

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.62
HSD17B10 Q99714 1/20 0.62
TDP1 Q9NUW8 1/20 0.62
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
CYP3A4 P08684 2/20 0.44
ATM Q13315 1/20 0.44
KDM4E B2RXH2 5/20 0.44
MAPT P10636 2/20 0.43
GABRA1 P14867 2/20 0.43
GABRB2 P47870 2/20 0.43
LMNA P02545 1/20 0.43
ADAM17 P78536 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
TRPM8 Q7Z2W7 1/20 0.43
HPGD P15428 3/20 0.43
NPC1 O15118 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperonal SCHEMBL5277282 0.92 ALDH1A1 (0.59) ALDH1A1HSD17B10TDP1CRHBPCRHR2
Piperonal SCHEMBL358063 0.90 ALDH1A1 (0.56) ALDH1A1HSD17B10TDP1CRHBPCRHR2
Piperonal SCHEMBL1774149 0.87 ALDH1A1 (0.82) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL433405 0.84 ALDH1A1 (0.49) ALDH1A1HSD17B10TDP1CRHBPCRHR2
Piperonal SCHEMBL9424697 0.81 ALDH1A1 (0.72) ALDH1A1HSD17B10TDP1CYP3A4ATM
Isosafrole SCHEMBL5688035 0.80 CYP3A4 (0.66) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL5839673 0.79 ALDH1A1 (0.79) ALDH1A1HSD17B10TDP1CRHBPCRHR2
Piperonal SCHEMBL28534378 0.79 ALDH1A1 (0.85) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL29411164 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL1864802 0.79 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 83 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190209441-A1 GEL NETWORK HAIR TREATMENT COMPOSITIONS WITH REDUCED ODOR WELLA OPERATIONS US, LLC 2019-07-11 US claimed
US-20190192408-A1 COMPOSITION FOR THE PERMANENT DEFORMATION OF HAIR HAVING REDUCED ODOUR WELLA OPERATIONS US, LLC 2019-06-27 US claimed
US-20190175476-A1 HAIR COLORING OR BLEACHING COMPOSITION WITH REDUCED ODOR WELLA OPERATIONS US, LLC 2019-06-13 US claimed
WO-2018053183-A1 COMPOSITION FOR THE PERMANENT DEFORMATION OF HAIR HAVING REDUCED ODOUR NOXELL CORPORATION (US) 2018-03-22 WO claimed
WO-2018053065-A1 COMPOSITION FOR THE PERMANENT DEFORMATION OF HAIR HAVING REDUCED ODOUR THE PROCTER & GAMBLE COMPANY (US) 2018-03-22 WO claimed
EP-3295925-A1 COMPOSITION FOR THE PERMANENT DEFORMATION OF HAIR HAVING REDUCED ODOUR Noxell Corporation (US) 2018-03-21 EP claimed
WO-2018048924-A1 GEL NETWORK HAIR TREATMENT COMPOSITIONS WITH REDUCED ODOR NOXELL CORPORATION (US) 2018-03-15 WO claimed
WO-2018048933-A1 HAIR COLORING OR BLEACHING COMPOSITION WITH REDUCED ODOR NOXELL CORPORATION (US) 2018-03-15 WO claimed
EP-3290085-A1 HAIR COLOURING OR BLEACHING COMPOSITION WITH REDUCED ODOUR Noxell Corporation (US) 2018-03-07 EP claimed
EP-3290086-A1 GEL NETWORK HAIR TREATMENT COMPOSITIONS WITH REDUCED ODOUR Noxell Corporation (US) 2018-03-07 EP claimed
US-20180010079-A1 LIQUID DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY 2018-01-11 US claimed
WO-2018009374-A1 LIQUID DETERGENT COMPOSITION THE PROCTER & GAMBLE COMPANY (US) 2018-01-11 WO claimed
EP-3266861-A1 LIQUID DETERGENT COMPOSITION The Procter & Gamble Company (US) 2018-01-10 EP claimed
CN-101688163-A Perfumed household products and methods for preserving perfume integrity and extending fragrance life PROCTER & GAMBLE 2010-03-31 CN claimed
US-5626852-A HYDROLYSIS OF ACETAL AND/OR KETAL THE MENNEN COMPANY (US) 1997-05-06 US claimed
CN-110769804-B Composition for improving smell 西姆莱斯股份公司 2024-01-05 CN disclosed
US-11779530-B2 Composition for the permanent deformation of hair having reduced odor WELLA OPERATIONS US, LLC (US) 2023-10-10 US disclosed
CN-1732019-A Deodorant composition TAKASAGO PERFUMERY CO LTD (JP) 2006-02-08 CN disclosed
EP-1561476-A1 DEODORANT COMPOSITION Takasago International Corporation (JP) 2005-08-10 EP disclosed
US-3936438-A INOTROPIC WARNER-LAMBERT COMPANY (US) 1976-02-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190192408-A1 COMPOSITION FOR THE PERMANENT DEFORMATION OF HAIR HAVING REDUCED ODOUR MAL2, MSH6, OR51E2 ALDH1A1 33/4885HSD17B10 739/4885TDP1 3156/4885
US-11779530-B2 Composition for the permanent deformation of hair having reduced odor OR51E2, MAL2, OR10J3 ALDH1A1 24/4885HSD17B10 519/4885TDP1 3731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.