Piperonal

Piperonal

SCHEMBL1774149

CCCC.O=Cc1ccc2c(c1)OCO2

nearest known ligand 0.82

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.82
HSD17B10 Q99714 2/20 0.82
TDP1 Q9NUW8 1/20 0.82
CYP3A4 P08684 2/20 0.56
ATM Q13315 1/20 0.56
TRPM8 Q7Z2W7 2/20 0.52
KDM4E B2RXH2 3/20 0.52
MAPT P10636 2/20 0.52
LMNA P02545 1/20 0.52
ADAM17 P78536 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
GABRA1 P14867 2/20 0.50
GABRG2 P18507 2/20 0.50
GABRB3 P28472 2/20 0.50
GABRA3 P34903 2/20 0.50
GABRA2 P47869 2/20 0.50
GABRB2 P47870 2/20 0.50
DYRK3 O43781 1/20 0.49
PIM1 P11309 1/20 0.49
CSNK2A2 P19784 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Piperonal SCHEMBL5839673 0.91 ALDH1A1 (0.79) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL29318 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL29411164 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL1864802 0.91 ALDH1A1 (1.00) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL5958791 0.89 ALDH1A1 (0.96) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL28017062 0.89 ALDH1A1 (0.96) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL6905345 0.88 ALDH1A1 (0.68) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL28534378 0.87 ALDH1A1 (0.85) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL873083 0.87 ALDH1A1 (0.62) ALDH1A1HSD17B10TDP1CYP3A4ATM
Piperonal SCHEMBL16161395 0.86 ALDH1A1 (0.82) ALDH1A1HSD17B10TDP1CYP3A4ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018053183-A1 COMPOSITION FOR THE PERMANENT DEFORMATION OF HAIR HAVING REDUCED ODOUR NOXELL CORPORATION (US) 2018-03-22 WO claimed
EP-3290086-A1 GEL NETWORK HAIR TREATMENT COMPOSITIONS WITH REDUCED ODOUR Noxell Corporation (US) 2018-03-07 EP claimed
US-20170121633-A1 Fragrance Compositions Comprising Ionic Liquids THE PROCTER & GAMBLE COMPANY 2017-05-04 US disclosed
US-8357649-B2 Delivery particle THE PROCTER & GAMBLE COMPANY (US) 2013-01-22 US disclosed
EP-2496682-A1 DELIVERY PARTICLE The Procter & Gamble Company (US) 2012-09-12 EP disclosed
US-20110107524-A1 DELIVERY PARTICLE THE PROCTER & GAMBLE COMPANY 2011-05-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170121633-A1 Fragrance Compositions Comprising Ionic Liquids CUTA, TRPA1, POLR1C ALDH1A1 1168/4885HSD17B10 1257/4885TDP1 2694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.