Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.33 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425765 | 0.77 | DUT (0.37) | TSHRSMN1; SMN2 | |
| SCHEMBL336528 | 0.74 | DUT (0.33) | — | |
| SCHEMBL4744132 | 0.73 | ALDH1A1 (0.41) | TSHRHTTSMN1; SMN2GAAALDH1A1 | |
| SCHEMBL8151339 | 0.72 | TSHR (0.44) | TSHRSMN1; SMN2 | |
| SCHEMBL13075717 | 0.72 | TSHR (0.40) | TSHRLPAR1RECQLCNR1CNR2 | |
| SCHEMBL3860740 | 0.71 | MTNR1A (0.34) | TSHR | |
| SCHEMBL25574184 | 0.71 | TSHR (0.36) | TSHRSMN1; SMN2GAA | |
| SCHEMBL15863147 | 0.71 | POLB (0.37) | ALDH1A1 | |
| SCHEMBL5847954 | 0.71 | DUT (0.33) | TSHRSMN1; SMN2 | |
| SCHEMBL10181980 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348890-A | In an aqueous solvent | NOF CORPORATION (JP) | 1994-09-20 | — | — | US | disclosed |
| EP-0545367-A1 | Trioxane derivatives, process for the preparation thereof, and method for the chemiluminescence | NOF CORPORATION (JP) | 1993-06-09 | — | — | EP | disclosed |