Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 3/20 | 0.36 |
| ▸ | MMP3 | P08254 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10175130 | 0.78 | MTNR1A (0.58) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL10175212 | 0.77 | MTNR1A (0.50) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL12610426 | 0.77 | MAOA (0.57) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL24088816 | 0.75 | MAOA (0.61) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL5314709 | 0.75 | MAOA (0.61) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL13074353 | 0.75 | MAOA (0.61) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL12446353 | 0.75 | MTNR1A (0.48) | MTNR1AMTNR1BMAOAMAOBALDH1A1 | |
| SCHEMBL10175188 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL14490649 | 0.73 | MAOA (0.68) | MTNR1AMTNR1BFFAR1MAOAMAOB | |
| SCHEMBL726437 | 0.73 | MTNR1A (0.47) | MTNR1AMTNR1BFFAR1ALDH1A1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0594621-A1 | PROCESS FOR ENZYMATICALLY PREPARING ENANTIOMER-FREE ESTERS AND ALCOHOLS | Roche Diagnostics GmbH (DE) | 1994-05-04 | — | — | EP | disclosed |
| WO-1993002034-A1 | PROCESS FOR ENZYMATICALLY PREPARING ENANTIOMER-FREE ESTERS AND ALCOHOLS | BOEHRINGER MANNHEIM GMBH (DE) | 1993-02-04 | — | — | WO | disclosed |