Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.48 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737516 | 0.87 | HTR7 (0.58) | KDM1AMEN1KMT2AHTR7CARM1 | |
| SCHEMBL4932045 | 0.83 | DPP7 (0.58) | KDM1AMEN1KMT2AHTR7CARM1 | |
| Hydrochloric Acid SCHEMBL5753957 | 0.81 | DPP7 (0.56) | KDM1AMEN1KMT2AHTR7CARM1 | |
| SCHEMBL8673780 | 0.81 | POLB (0.59) | MEN1KMT2AACHEALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL11614221 | 0.80 | DPP7 (0.54) | KDM1AMEN1KMT2AHTR7CARM1 | |
| Hydrochloric Acid SCHEMBL11093613 | 0.80 | POLB (0.58) | MEN1KMT2AACHEALDH1A1ADRA2A | |
| SCHEMBL7672095 | 0.79 | SIGMAR1 (0.53) | KDM1AMEN1KMT2AHTR7CARM1 | |
| SCHEMBL5549334 | 0.79 | MEN1 (0.68) | MEN1KMT2AACHEMAPTPOLB | |
| SCHEMBL17654095 | 0.77 | HTR7 (0.74) | HTR7 | |
| SCHEMBL12311335 | 0.76 | ADORA2A (0.50) | KDM1AMEN1KMT2AHTR7CARM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5296483-A | Antidepressant | UNIVERSITY OF FLORIDA (US) | 1994-03-22 | — | — | US | disclosed |
| US-5082853-A | Drug delivery | BODOR NICHOLAS S (US) | 1992-01-21 | — | — | US | disclosed |
| US-4933438-A | Brain-specific analogues of centrally acting amines | UNIVERSITY OF FLORIDA (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0174342-B1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1989-12-20 | — | — | EP | disclosed |
| US-4771059-A | CENTRAL NERVOUS SYSTEM | UNIVERSITY OF FLORIDA (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0100717-B1 | PROCESS FOR THE PREPARATION OF ALPHAALKYLAMINOALDEHYDES | SANOFI S.A. (FR) | 1985-11-06 | — | — | EP | disclosed |