SCHEMBL9425720

SCHEMBL9425720

CC(=C[Si](C)(C)C1CCCCO1)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM1A O60341 1/20 0.36
GAA P10253 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
SLC6A3 Q01959 2/20 0.35
HPGD P15428 2/20 0.34
ALDH1A1 P00352 2/20 0.31
POLB P06746 1/20 0.31
ADRB2 P07550 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
MGLL Q99685 1/20 0.30
HTT P42858 1/20 0.30
GLA P06280 1/20 0.30
ALOX12 P18054 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1694302 0.73 ALDH1A1 (0.39) SMN1; SMN2SLC6A3ALDH1A1MGLL
SCHEMBL7057380 0.72 LMNA (0.37) SMN1; SMN2SLC6A3HPGDALDH1A1
SCHEMBL22772276 0.71 ALDH1A1 (0.40) KDM1AGAASMN1; SMN2SLC6A3HPGD
SCHEMBL28814281 0.71 SLC6A3 (0.36) GAASMN1; SMN2L3MBTL1SLC6A3HPGD
SCHEMBL2233581 0.71 SLC6A3 (0.38) GAASMN1; SMN2L3MBTL1SLC6A3HPGD
SCHEMBL28857357 0.70 SLC6A3 (0.38) GAASMN1; SMN2SLC6A3HPGDALDH1A1
SCHEMBL4454467 0.70 KDM1A (0.36) KDM1AGAASMN1; SMN2L3MBTL1SLC6A3
SCHEMBL629741 0.69 SLC6A3 (0.37) GAASMN1; SMN2SLC6A3HPGDALDH1A1
SCHEMBL11874879 0.68 HPGD (0.35) KDM1AGAASMN1; SMN2SLC6A3HPGD
SCHEMBL1071706 0.67 KDM1A (0.42) KDM1ASMN1; SMN2HPGDALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5330823-A Transparent recording sheets XEROX CORPORATION (US) 1994-07-19 US disclosed