SCHEMBL9425807

SCHEMBL9425807

COc1cc(-c2nc(-c3ccc(N(C)C)cc3)c(C)[nH]2)cc(OC)c1OC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 6/20 0.52
AMY1A P0DUB6 2/20 0.43
NOX1 Q9Y5S8 3/20 0.39
SIRT2 Q8IXJ6 1/20 0.39
SIRT1 Q96EB6 1/20 0.39
BRD4 O60885 1/20 0.38
MPO P05164 1/20 0.38
SLC9A1 P19634 1/20 0.38
TP53 P04637 1/20 0.38
MAPT P10636 1/20 0.38
PARP1 P09874 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9426226 0.90 AMY1A (0.53) SMPD3AMY1ANOX1SIRT2SIRT1
SCHEMBL9425971 0.89 SMPD3 (0.54) SMPD3AMY1ANOX1MPOTP53
SCHEMBL9331183 0.84 SMPD3 (0.73) SMPD3AMY1ANOX1TP53MAPT
SCHEMBL9425988 0.84 SMPD3 (0.51) SMPD3NOX1TP53MAPT
Hydrochloric Acid SCHEMBL1735170 0.83 SMPD3 (0.71) SMPD3AMY1ANOX1TP53MAPT
SCHEMBL9188234 0.82 SMPD3 (0.54) SMPD3AMY1ANOX1SIRT2SIRT1
SCHEMBL3623105 0.81 ALOX5 (0.41) SMPD3AMY1ANOX1MPOTP53
SCHEMBL9425781 0.81 SMPD3 (0.47) SMPD3AMY1ANOX1SIRT2SIRT1
SCHEMBL9425243 0.81 NOX1 (0.58) SMPD3NOX1PARP1
Hydrochloric Acid SCHEMBL9426019 0.80 NOX1 (0.57) SMPD3NOX1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5292669-A Chromogenic agent, oxidizer BOEHRINGER MANNHEIM GMBH (DE) 1994-03-08 US claimed
US-5292669-A Chromogenic agent, oxidizer BOEHRINGER MANNHEIM GMBH (DE) 1994-03-08 US disclosed