Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425697 | 0.96 | HPGD (0.54) | HPGDPYGLHSD17B10TRPV1MEN1 | |
| SCHEMBL9425790 | 0.95 | HPGD (0.53) | HPGDPYGLHSD17B10TRPV1MEN1 | |
| SCHEMBL9425938 | 0.79 | KMT2A (0.60) | TRPV1KMT2A | |
| SCHEMBL9425990 | 0.79 | HPGD (0.54) | HPGDPYGLTRPV1MAPTKMT2A | |
| SCHEMBL10752702 | 0.78 | CYP3A4 (0.43) | MAPT | |
| SCHEMBL9424396 | 0.77 | ALOX5 (0.40) | KMT2A | |
| SCHEMBL9425705 | 0.76 | TRPV1 (0.60) | HPGDTRPV1MEN1KMT2A | |
| SCHEMBL9425968 | 0.76 | HPGD (0.51) | HPGDPYGLHSD17B10TRPV1MEN1 | |
| SCHEMBL9425794 | 0.75 | TRPV1 (0.62) | HPGDPYGLHSD17B10TRPV1MEN1 | |
| SCHEMBL9425972 | 0.74 | TRPM8 (0.38) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338745-A | Alzheimer's disease | MITSUI TOATSU CHEMICALS, INCORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0495998-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |