Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10752702 | 0.81 | CYP3A4 (0.43) | TRPM8RAB9AL3MBTL1 | |
| SCHEMBL7835653 | 0.79 | FFAR1 (0.43) | TRPM8 | |
| SCHEMBL9425976 | 0.77 | TRPM8 (0.62) | TRPM8KMT2ARAB9A | |
| SCHEMBL9424396 | 0.77 | ALOX5 (0.40) | KMT2A | |
| SCHEMBL9425935 | 0.74 | HPGD (0.49) | KMT2A | |
| SCHEMBL9425697 | 0.73 | HPGD (0.54) | KMT2A | |
| SCHEMBL9137648 | 0.72 | TAAR1 (0.32) | — | |
| SCHEMBL9425790 | 0.72 | HPGD (0.53) | KMT2ARAB9A | |
| SCHEMBL4673253 | 0.72 | ALDH1A1 (0.36) | RAB9AL3MBTL1 | |
| SCHEMBL9579912 | 0.70 | KDM4E (0.36) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338745-A | Alzheimer's disease | MITSUI TOATSU CHEMICALS, INCORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0495998-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |