Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | IAPP | P10997 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9426166 | 0.81 | TRPM8 (0.48) | CDK8CLK4RAB9ATRPM8KMT2A | |
| SCHEMBL9425827 | 0.81 | CDK8 (0.39) | CDK8CLK4NPC1SMN1; SMN2RAB9A | |
| SCHEMBL15243134 | 0.79 | ALOX15 (0.41) | NPC1SMN1; SMN2ALOX15ALOX12RAB9A | |
| SCHEMBL9588857 | 0.77 | ALOX15 (0.48) | NPC1ALOX15ALOX12RAB9A | |
| SCHEMBL9346628 | 0.77 | IAPP (0.62) | NPC1SMN1; SMN2ALOX15RAB9AIAPP | |
| SCHEMBL9425968 | 0.77 | HPGD (0.51) | KMT2A | |
| SCHEMBL9425817 | 0.76 | TRPM8 (0.41) | CDK8CLK4NPC1SMN1; SMN2RAB9A | |
| SCHEMBL25020569 | 0.76 | ALOX15 (0.48) | NPC1SMN1; SMN2ALOX15ALOX12RAB9A | |
| SCHEMBL5346679 | 0.76 | ALOX15 (0.48) | NPC1SMN1; SMN2ALOX15ALOX12RAB9A | |
| SCHEMBL30932929 | 0.76 | ALOX15 (0.48) | NPC1SMN1; SMN2ALOX15ALOX12RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5338745-A | Alzheimer's disease | MITSUI TOATSU CHEMICALS, INCORPORATION (JP) | 1994-08-16 | — | — | US | disclosed |
| EP-0495998-A1 | DIHYDROCAFFEIC ACID AMIDE DERIVATIVE AND APPLICATION THEREOF AS MEDICINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-07-29 | — | — | EP | disclosed |