Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9425270 | 0.90 | ABCB1 (0.64) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL9815800 | 0.89 | POLB (0.56) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL8173237 | 0.87 | POLB (0.68) | CYP3A4POLBCYP2C9 | |
| SCHEMBL9425963 | 0.83 | ABCB1 (0.64) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL9511093 | 0.82 | AGTR1 (0.55) | CYP3A4POLBCYP2C9 | |
| SCHEMBL9509589 | 0.82 | MEN1 (0.57) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL9511092 | 0.81 | POLB (0.77) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL9426147 | 0.81 | POLB (0.56) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL9425189 | 0.81 | HPGD (0.68) | ABCB1CYP3A4POLBCYP2C9 | |
| SCHEMBL9815793 | 0.80 | ABCB1 (0.62) | ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0253468-B1 | SIX-MEMBERED HETEROCYCLIC DERIVATIVES OF N'SUBSTITUTED-N,N'-DIACYLHYDRAZINES | ROHM AND HAAS COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |