Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | MTOR | P42345 | 2/20 | 0.36 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662216 | 0.95 | GAA (0.41) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10569523 | 0.76 | GAA (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL11043791 | 0.74 | GAA (0.49) | GAACDK1MAPTTP53GLA | |
| SCHEMBL8537555 | 0.72 | GAA (0.54) | GAACDK1MAPTTP53GLA | |
| SCHEMBL9809038 | 0.71 | GAA (0.46) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10616134 | 0.71 | GAA (0.67) | GAACDK1MAPTTP53GLA | |
| SCHEMBL11041517 | 0.71 | GAA (0.55) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10566127 | 0.71 | SMN1; SMN2 (0.46) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10568375 | 0.71 | KDM4E (0.51) | GAACDK1MAPTTP53GLA | |
| SCHEMBL10665487 | 0.71 | GAA (0.52) | GAACDK1MAPTTP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5356862-A | Herbicidal sulfonylureas | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-10-18 | — | — | US | disclosed |