Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10974258 | 0.94 | GAA (0.44) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL11037886 | 0.89 | ALDH1A1 (0.39) | GAAMAPTTP53KDM4EALDH1A1 | |
| SCHEMBL11045447 | 0.89 | GAA (0.40) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL11041438 | 0.88 | KDM4E (0.39) | GAAKDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11040008 | 0.86 | ALDH1A1 (0.36) | GAAMAPTKDM4EALDH1A1HPGD | |
| SCHEMBL10569523 | 0.84 | GAA (0.51) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10566127 | 0.79 | SMN1; SMN2 (0.46) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10568375 | 0.79 | KDM4E (0.51) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL10971549 | 0.78 | GAA (0.50) | GAAMAPTTP53GLACDK1 | |
| SCHEMBL9426154 | 0.74 | GAA (0.46) | GAAMAPTTP53GLACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0070698-B1 | HERBICIDAL INDOLE SULFONAMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-11-13 | — | — | EP | claimed |