Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3903336 | 0.85 | PDE10A (0.54) | ALDH1A1SMN1; SMN2KDM4EPOLBDHODH | |
| SCHEMBL9426414 | 0.82 | DHODH (0.44) | DHODHPDE10ATSHRPRNPPPARG | |
| SCHEMBL9426410 | 0.76 | MAPT (0.44) | ALDH1A1KDM4EPOLBMAPTMEN1 | |
| SCHEMBL3333058 | 0.75 | IGFBP3 (0.47) | ALDH1A1KDM4EELANETPMTIGFBP3 | |
| SCHEMBL13024501 | 0.75 | KDM4E (0.43) | ALDH1A1KDM4EPOLBL3MBTL1ELANE | |
| SCHEMBL21870 | 0.74 | KDM4E (0.55) | ALDH1A1MAPK1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL377596 | 0.74 | KDM4E (0.55) | ALDH1A1MAPK1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL6912704 | 0.72 | KDM4E (0.53) | ALDH1A1MAPK1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL17558193 | 0.72 | KDM4E (0.53) | ALDH1A1MAPK1SMN1; SMN2KDM4EPOLB | |
| SCHEMBL6917032 | 0.72 | KDM4E (0.53) | ALDH1A1MAPK1SMN1; SMN2KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321136-A | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-06-14 | — | — | US | disclosed |