Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 12/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9282972 | 0.81 | MAPT (0.49) | MAPTRAB9ANPSR1TDP1KDM4E | |
| Phosphine SCHEMBL28088577 | 0.80 | MAPT (0.48) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL3903336 | 0.77 | PDE10A (0.54) | KDM4EPOLBALDH1A1KMT2AMEN1 | |
| SCHEMBL9426671 | 0.76 | ALDH1A1 (0.43) | MAPTRAB9ANPSR1KDM4EPOLB | |
| SCHEMBL27470580 | 0.76 | POLB (0.49) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL9286049 | 0.76 | CYP3A4 (0.55) | MAPTRAB9ANPSR1TDP1POLB | |
| SCHEMBL7045154 | 0.72 | MAPT (0.56) | MAPTRAB9AKDM4EPOLBNPC1 | |
| SCHEMBL5705535 | 0.72 | MAPT (0.50) | MAPTRAB9ANPSR1TDP1KDM4E | |
| SCHEMBL7046974 | 0.71 | TP53 (0.59) | MAPTRAB9ANPSR1POLBNPC1 | |
| SCHEMBL3905891 | 0.71 | POLB (0.38) | MAPTRAB9ANPSR1TDP1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5321136-A | Peri substituted fused ring chemiluminescent labels and their conjugates, and assays therefrom | LONDON DIAGNOSTICS, INC. (US) | 1994-06-14 | — | — | US | disclosed |