Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.49 |
| ▸ | BACE1 | P56817 | 4/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9632755 | 0.77 | ACHE (0.51) | ACHEBACE1BCHESIGMAR1CHRM4 | |
| SCHEMBL8100648 | 0.73 | SIGMAR1 (0.52) | ACHEBACE1BCHESIGMAR1 | |
| SCHEMBL8114810 | 0.73 | ACHE (0.51) | ACHEBACE1BCHESIGMAR1 | |
| SCHEMBL30763093 | 0.73 | ACHE (0.55) | ACHEBACE1BCHESIGMAR1 | |
| SCHEMBL28657725 | 0.73 | CCR3 (0.57) | ACHEBACE1BCHE | |
| SCHEMBL9408575 | 0.72 | ACHE (0.51) | ACHEBACE1BCHESIGMAR1 | |
| SCHEMBL9408572 | 0.72 | ACHE (0.51) | ACHEBACE1BCHESIGMAR1 | |
| SCHEMBL803083 | 0.71 | CCR3 (0.58) | ACHEBACE1BCHE | |
| SCHEMBL1812265 | 0.71 | CCR3 (0.59) | ACHEBACE1BCHESIGMAR1 | |
| SCHEMBL9426673 | 0.71 | ACHE (0.51) | ACHEBACE1BCHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5348968-A | Migraines | ADIR ET COMPAGNIE (FR) | 1994-09-20 | — | — | US | disclosed |