Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.51 |
| ▸ | BCHE | P06276 | 2/20 | 0.51 |
| ▸ | BACE1 | P56817 | 2/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9631980 | 0.92 | ALDH1A1 (0.50) | ACHEBCHEBACE1DRD2DRD4 | |
| Water SCHEMBL10719501 | 0.83 | BCHE (0.49) | ACHEBCHEBACE1SLC6A3SLC6A4 | |
| SCHEMBL10519952 | 0.83 | CCR3 (0.59) | ACHEBCHE | |
| SCHEMBL7365667 | 0.80 | DRD2 (0.50) | CHRM4DRD2SIGMAR1 | |
| SCHEMBL10460719 | 0.80 | KCNH2 (0.59) | ACHEBCHEBACE1DRD2DRD4 | |
| SCHEMBL28657725 | 0.78 | CCR3 (0.57) | ACHEBCHEBACE1 | |
| SCHEMBL9426679 | 0.77 | ACHE (0.49) | ACHEBCHEBACE1CHRM4SIGMAR1 | |
| SCHEMBL803083 | 0.77 | CCR3 (0.58) | ACHEBCHEBACE1 | |
| SCHEMBL7442047 | 0.76 | KCNH2 (0.69) | ACHEBCHEBACE1SLC6A12TMEM97 | |
| SCHEMBL7366392 | 0.76 | DRD2 (0.55) | CHRM4DRD2SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079249-A | Serotine antagonists at 5-HT2 level, antiallergens, antihistamines | ADIR ET COMPAGNIE (FR) | 1992-01-07 | — | — | US | disclosed |
| US-5071847-A | BIS (ARYL) ALKENE COMPOUNDS OF HOMOPIPERIDINES USEFUL AS SEROTONIN-ANTAGONISTS | ADIR ET COMPAGNIE (FR) | 1991-12-10 | — | — | US | disclosed |
| US-5028607-A | Antiserotonine agents | ADIR ET COMPAGNIE (FR) | 1991-07-02 | — | — | US | disclosed |