SCHEMBL942695

SCHEMBL942695

NCCC(N)CN1CCN(CCN)CC1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.56
ACE2 Q9BYF1 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
KEAP1 Q14145 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ALDH1A1 P00352 1/20 0.30
SLC6A4 P31645 2/20 0.30
SLC6A3 Q01959 2/20 0.30
PRMT3 O60678 1/20 0.30
CARM1 Q86X55 1/20 0.30
PRMT6 Q96LA8 1/20 0.30
PRMT1 Q99873 1/20 0.30
PRMT8 Q9NR22 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5614306 0.86 ALOX15 (0.39) ALOX15ACE2
SCHEMBL990900 0.81 ALOX15 (0.54) ALOX15ACE2SIGMAR1ALDH1A1SLC6A4
SCHEMBL21117097 0.81 ALOX15 (0.54) ALOX15ACE2SIGMAR1ALDH1A1SLC6A4
SCHEMBL1682206 0.79 ALOX15 (0.65) ALOX15ACE2SIGMAR1KEAP1SMN1; SMN2
SCHEMBL22248563 0.77 SMN1; SMN2 (0.36) SIGMAR1SMN1; SMN2
SCHEMBL2945288 0.77 SMN1; SMN2 (0.36) SIGMAR1SMN1; SMN2
SCHEMBL28776943 0.77 KMT2A (0.48) ALOX15ALDH1A1
SCHEMBL991986 0.76 ALOX15 (0.59) ALOX15ACE2SIGMAR1KEAP1SMN1; SMN2
SCHEMBL13833162 0.76 ALOX15 (0.59) ALOX15ACE2SIGMAR1KEAP1SMN1; SMN2
SCHEMBL10447876 0.76 ALOX15 (0.59) ALOX15ACE2SIGMAR1KEAP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 222 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118019833-A Polyamide fuel additives 雪佛龙美国公司 2024-05-10 CN claimed
CN-113195658-A Polishing slurry composition for STI process 凯斯科技股份有限公司 2021-07-30 CN claimed
US-20200190390-A1 ADDITIVE TO FLEXIBILIZE EPOXY-BASED RESINS FOR USE IN OIL FIELD APPLICATIONS COVESTRO LLC 2020-06-18 US claimed
WO-2019036189-A1 ADDITIVE TO FLEXIBILIZE EPOXY-BASED RESINS FOR USE IN OIL FIELD APPLICATIONS COVESTRO LLC (US) 2019-02-21 WO claimed
US-8765008-B2 Hydroxyalkylated polyalkylenepolyamine composition, method for producing same and method for producing polyurethane resin using such hydroxyalkylated polyalkylenepolyamine composition TOSOH CORPORATION (JP) 2014-07-01 US claimed
EP-4745170-A1 METHOD FOR PREPARING A URETHANE GROUP-CONTAINING POLYMER BASF SE (DE) 2026-05-20 EP disclosed
EP-4745169-A1 COMPOSITION USEFUL AS COATING, SEALANT OR ADHESIVE BASF SE (DE) 2026-05-20 EP disclosed
EP-4340807-B1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MAT INC (US) 2026-01-28 EP disclosed
EP-3813991-B1 FLAT SHEET POROUS PVC MEMBRANE LUBRIZOL ADVANCED MAT INC (US) 2025-11-19 EP disclosed
US-20240279509-A1 WATER-BASED RADIATION-CURABLE COMPOSITION FOR SOFT FEEL APPLICATIONS ALLNEX USA INC. (US) 2024-08-22 US disclosed
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2024-08-01 US disclosed
CN-118019833-A Polyamide fuel additives 雪佛龙美国公司 2024-05-10 CN disclosed
US-4701480-A PARTIALLY DISPLACING THE VOLATILE BASE OF A NEUTRALIZED CARBOXY-CONTAINING HYDROPHILIC POLYMER BY REACTING WITH AN ALKALI METAL COMPOUND MOBAY CORPORATION (US) 1987-10-20 US disclosed
US-4677180-A DIALKYL MALONATE BLOCKED ISOCYANATE MOBAY CORPORATION (US) 1987-06-30 US disclosed
EP-0219677-A1 A process for the preparation of an aqueous polyurethane-urea dispersion MILES INC. (US) 1987-04-29 EP disclosed
EP-0148970-A2 Stable, aqueous dispersions of polyurethane-ureas and coatings and films prepared therefrom BAYER AG (DE) 1985-07-24 EP disclosed
US-4518522-A DI-(ALKYL OR ALKOXYALKYL) MALONATES AND CONTAINING A STABILIZING MONOFUNCTIONAL REACTIVE COMPOUND MOBAY CHEMICAL CORPORATION (US) 1985-05-21 US disclosed
US-4501852-A INCORPORATING ANIONIC GROJPS, HYDROPHILIC CHAINS MOBAY CHEMICAL CORPORATION (US) 1985-02-26 US disclosed
US-4439593-A Polyurethane compositions with improved storage stability MOBAY CHEMICAL CORPORATION (US) 1984-03-27 US disclosed
US-4408008-A COATINGS, ADHESIVES MOBAY CHEMICAL CORPORATION (US) 1983-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240252419-A1 HAIR COLOR COMPOSITIONS FOR MITIGATING COLOR LOSS TYR, DOT1L, CUTA ALOX15 4286/4885ACE2 4046/4885SIGMAR1 4201/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.