Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2945288 | 1.00 | SMN1; SMN2 (0.36) | SMN1; SMN2ANPEPERAP2POLBRAD52 | |
| SCHEMBL27698375 | 0.82 | ACE2 (0.40) | SMN1; SMN2ANPEPERAP2CXCR4 | |
| SCHEMBL10386726 | 0.82 | SMN1; SMN2 (0.39) | SMN1; SMN2ANPEPERAP2POLBRAD52 | |
| SCHEMBL6659615 | 0.82 | POLB (0.39) | SMN1; SMN2ANPEPERAP2POLBRAD52 | |
| SCHEMBL9845960 | 0.79 | SIGMAR1 (0.41) | SMN1; SMN2CXCR4CHRM5CHRM3SIGMAR1 | |
| Ethylenediamine SCHEMBL9064149 | 0.78 | SMN1; SMN2 (0.38) | SMN1; SMN2ANPEPERAP2POLBRAD52 | |
| SCHEMBL7428169 | 0.77 | SMN1; SMN2 (0.39) | SMN1; SMN2CXCR4CHRM5CHRM3SIGMAR1 | |
| SCHEMBL942695 | 0.77 | ALOX15 (0.56) | SMN1; SMN2SIGMAR1 | |
| SCHEMBL991697 | 0.77 | SMN1; SMN2 (0.44) | SMN1; SMN2ANPEPERAP2POLBRAD52 | |
| SCHEMBL8761347 | 0.76 | GNAO1 (0.41) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020150372-A1 | ANTIMICROBIAL COMPOUNDS AND METHODS | CURZA GLOBAL, LLC (US) | 2020-07-23 | — | — | WO | disclosed |