Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | KHK | P50053 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1775878 | 0.74 | HRH4 (0.52) | HRH4KCNH2HRH3NUDT1 | |
| SCHEMBL19637221 | 0.71 | ADRB1 (0.47) | HRH4KCNH2HRH3KDM4EALDH1A1 | |
| SCHEMBL18484592 | 0.68 | HTR2C (0.45) | KDM4EALDH1A1HTR2C | |
| SCHEMBL22724626 | 0.67 | CHRNB2 (0.39) | HRH4KCNH2HRH3KDM4EALDH1A1 | |
| SCHEMBL7237642 | 0.67 | KDM4E (0.58) | HRH4KDM4EALDH1A1TDP1HRH1 | |
| SCHEMBL3621162 | 0.66 | HTR2C (0.46) | HRH4KCNH2HRH3NUDT1HRH1 | |
| SCHEMBL22994710 | 0.65 | NUDT1 (0.41) | HRH4KCNH2HRH3KDM4EALDH1A1 | |
| SCHEMBL6656229 | 0.65 | GCGR (0.32) | — | |
| SCHEMBL10481275 | 0.65 | HRH4 (0.37) | HRH4KCNH2HRH3KDM4EALDH1A1 | |
| SCHEMBL10481273 | 0.65 | HRH4 (0.43) | HRH4KCNH2HRH3KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5302719-A | Antiinflammatory and antioxidant | ROUSSEL UCLAF (FR) | 1994-04-12 | — | — | US | disclosed |