Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449606 | 0.85 | CYP11B1 (0.39) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL8080634 | 0.83 | MEN1 (0.46) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL10525309 | 0.78 | ESR1 (0.45) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL10382097 | 0.77 | MAOB (0.43) | MEN1GAAMAPTKMT2AALDH1A1 | |
| SCHEMBL9353374 | 0.76 | CYP11B1 (0.38) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL8807255 | 0.74 | RARB (0.59) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL24125046 | 0.73 | KIF11 (0.39) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL10024823 | 0.73 | KIF11 (0.39) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL8992639 | 0.73 | GABRA1 (0.44) | GABRA1GABRB2CNR2MEN1GAA | |
| SCHEMBL9245694 | 0.73 | NPC1 (0.65) | GABRA1GABRB2CNR2MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340497-A | Ferroelectric liquid crystal | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1994-08-23 | — | — | US | disclosed |
| EP-0428665-A1 | FLUOROPHENYL PYRIMIDINES. | MERCK PATENT GMBH (DE) | 1991-05-29 | — | — | EP | disclosed |
| WO-1990015116-A1 | FLUOROPHENYL PYRIMIDINES | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1990-12-13 | — | — | WO | disclosed |