Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9427521 | 0.98 | KDM4E (0.41) | NPC1RAB9ASMN1; SMN2TRPC6MEN1 | |
| SCHEMBL7343184 | 0.89 | KCNH2 (0.49) | NPC1RAB9ASMN1; SMN2TRPC6MEN1 | |
| SCHEMBL7370495 | 0.88 | MAPK14 (0.42) | NPC1RAB9ASMN1; SMN2TRPC6MEN1 | |
| Oxalic Acid SCHEMBL9427500 | 0.87 | KDM4E (0.47) | SMN1; SMN2TRPC6MEN1KMT2ASMPD1 | |
| Fumaric Acid SCHEMBL9427555 | 0.85 | MAPK14 (0.40) | NPC1RAB9ASMN1; SMN2TRPC6MEN1 | |
| Fumaric Acid SCHEMBL9427564 | 0.85 | MAPK14 (0.40) | NPC1RAB9ASMN1; SMN2TRPC6MEN1 | |
| SCHEMBL9803091 | 0.82 | KDM4E (0.46) | SMN1; SMN2ADRB2MAPK14LMNAADRB1 | |
| SCHEMBL7341049 | 0.82 | MAPK14 (0.43) | NPC1RAB9ASMN1; SMN2TRPC6MEN1 | |
| SCHEMBL7343376 | 0.82 | SMN1; SMN2 (0.43) | NPC1RAB9ASMN1; SMN2TRPC6MEN1 | |
| Oxalic Acid SCHEMBL9803165 | 0.81 | KDM4E (0.49) | SMN1; SMN2MEN1KMT2AADRB2MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373023-A | Antiischaemic agent | SYNTHELABO (FR) | 1994-12-13 | — | — | US | disclosed |