Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7343184 | 0.98 | KCNH2 (0.49) | KDM4EALDH1A1KCNH2SMPD1SMN1; SMN2 | |
| Oxalic Acid SCHEMBL9427521 | 0.90 | KDM4E (0.41) | KDM4EALDH1A1SMN1; SMN2TRPC6MEN1 | |
| SCHEMBL9427352 | 0.87 | NPC1 (0.42) | KCNH2SMPD1SMN1; SMN2TRPC6MEN1 | |
| Oxalic Acid SCHEMBL9803157 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1KCNH2SMPD1SMN1; SMN2 | |
| SCHEMBL9427512 | 0.82 | SMPD1 (0.40) | KDM4EALDH1A1KCNH2SMPD1CYP3A4 | |
| SCHEMBL9803095 | 0.81 | KCNH2 (0.44) | KDM4EALDH1A1KCNH2SMPD1SMN1; SMN2 | |
| SCHEMBL7343376 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1SMN1; SMN2TRPC6MEN1KMT2A | |
| SCHEMBL7370495 | 0.80 | MAPK14 (0.42) | ALDH1A1SMN1; SMN2TRPC6MEN1KMT2A | |
| SCHEMBL7341049 | 0.78 | MAPK14 (0.43) | ALDH1A1SMN1; SMN2TRPC6MEN1KMT2A | |
| Fumaric Acid SCHEMBL9427564 | 0.76 | MAPK14 (0.40) | ALDH1A1SMN1; SMN2TRPC6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5373023-A | Antiischaemic agent | SYNTHELABO (FR) | 1994-12-13 | — | — | US | disclosed |